43720
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43720
Fluka
N,N′-Disuccinimidyl carbonate
purum, ≥95.0% (NMR)
| Synonym: | N-Succinimidyl carbonate, Di(N-succinimidyl) carbonate, DSC |
| CAS Number: | 74124-79-1 |
| Linear Formula: | C9H8N2O7 |
| Molecular Weight: | 256.17 |
| Beilstein Registry Number: | 1499137 |
| EC Number: | 277-730-3 |
| MDL number: | MFCD00009767 |
| PubChem Substance ID: | 24867355 |
Description
| Other Notes | Convenient reagent for preparing N-succinimidyl esters of N-protected amino acids and other acids;1 activated carbonate, e.g. synthesis of ureas and carbamates;2,3 coupling of ligands to proteins (via lysines).4 |
Properties
| grade | purum |
| assay | ≥95.0% (NMR) |
| total impurities | ~3% N-hydroxysuccinimide (NMR) |
| mp | 190 °C (dec.)(lit.) |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
References
| Cited Reference | 1. T. Kokubo et al. J. Am. Chem. Soc. 109, 606, (1987) |
| 2. N. Nimura et al. Anal. Chem. 58, 2372, (1986) | |
| 3. A.K. Ghosh et al. Tetrahedron Lett. 33, 2781, (1992) | |
| 4. M. Morpurgo et al. J. Biochem. Biophys. Methods 38, 17, (1999) Abstract | |
| Fieser | Fieser 9,208 / Fieser 11,226 |
| reference | Aldrich MSDS 1, 837:C / Corp MSDS 1 (1), 1478:C / FT-IR 1 (1), 796:D / FT-IR 2 (1), 1352:B / RegBook 1 (1), 931:L / Structure Index 1, 145:C:3 |
